Computer modeling of gravity profiles of the Rome trough in eastern Kentucky, using data from deep wells in the area as constraints, has provided a general subsurface picture of the area, delineated several major basement features which may be of economic significance, and provided information concerning the areal extent of the trough. As shown in earlier studies, the trough is bounded on the north by the Kentucky River fault zone and its eastward subsurface extension; it is bounded on the south by several uplifts and basins. Older faulting associated with a large gravity high forms the western boundary of the Rome trough; to the east, the trough deepens as it enters West Virginia. The tectonic history of the region is complex and several episodes of rifting are suggested which include the formation of the Rome trough itself. However, a tectonic model to account for the specifics of the formation of the trough cannot be presently formulated because of lack of information in adjacent areas.