The connectivity and facies heterogeneity of low permeability, terminal deep-water lobes are important uncertainties in reservoir characterization and development. Deep-water lobes have been conceptualized as basinwide, sheet-like deposits. However, recent work has shown more complex 3D architecture and spatial variability of petrophysical properties, which can have significant impact on reservoir performance. We use high-resolution seismic-reflection data (dominant frequency ~40 Hz) from the shallow subsurface of the Niger Delta continental slope to illustrate the stratigraphic architecture and facies variability of a deep-water lobe system. The interval of interest is a package of high-amplitude seismic reflections that is lobate in plan view and externally mounded in cross section. This interval comprises at least three sub-packages of continuous, single- or multi-cycle seismic reflections, which locally exhibit bidirectional downlap and compensational stacking. Reflections bounding the uppermost sub-package represent channel avulsion, compensation and modification of initial deposits, unconfined deposition at the channel mouth, and downstream channel bifurcation. We place our interpretations within an architectural hierarchy and consider the impact of depositional heterogeneity on fluid flow behavior during hydrocarbon production. These interpretations inform the modeling and prediction of 3D heterogeneity of deep-water lobes and illustrate the importance of detailed characterization in order to understand reservoir connectivity and quality.