In this paper, we present comprehensive data on stress orientation and relative magnitude in areas throughout North America where unconventional oil and gas are currently being developed. We find excellent agreement between maximum horizontal principal stress (S_Hmax) orientations over a wide range of depths, using multiple methods. In all basins studied, we observed coherent stress fields that in some cases vary systematically from one part of a basin to another. In the Appalachian Basin in the eastern United States, S_Hmax is oriented northeast–southwest to east-northeast–west-southwest and the style of faulting is compressive, transitioning from reverse faulting in eastern Pennsylvania and New York to principally strike-slip faulting in western Pennsylvania, Ohio, and West Virginia. In the midcontinent, central Oklahoma is characterized by an approximately east–west S_Hmax direction and strike-slip faulting. The Fort Worth Basin in northeastern Texas is characterized by normal–strike-slip faulting and a north-northeast–south-southwest S_Hmax direction. In the Midland subbasin of western Texas, S_Hmax is consistently approximately east–west and normal–strike-slip faulting is observed. Farther west, the Delaware subbasin of western Texas and southeastern New Mexico is characterized by normal faulting and S_Hmax rotates ∼150° clockwise from north to south. Marked changes in S_Hmax direction also occur across the Raton Basin of southern Colorado and northern New Mexico, the Denver-Julesburg Basin in northern Colorado, and the Uinta Basin in northeastern Utah, likely associated with their location near the margins of extensional provinces. The new data sets we present help improve operational efficiency by constraining absolute stress magnitudes and the ideal azimuth to drill horizontal wells (i.e., perpendicular to the local S_Hmax orientation) and make it possible to predict which fractures and faults are likely to be activated during hydraulic stimulation.